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Whether directly or not, many subsequent novels and films are inspired by Levin's novel Rosemary's Baby... The Devil's Advocate (film) repeats Levin's plot-contrivances, in which another woman becomes a pawn for her husband's upward rise to fame; The Astronaut's Wife, is about a woman who is impregnated by an extraterrestrial-alien that has taken over the mind and body of her husband (Coincidentally, in both those films the subject wife is played by Charlize Theron). Similarly, the novels Lupe (1977) by Gene Thompson, and The Glow (1978) by Brooks Stanwood, share plot elements with Rosemary's Baby; the former story about a Hispanic hare-lipped boy who dabbles in the occult and reincarnates himself in the womb of his unwitting female host-victim, and the latter (in essence) about a coven of elderly New York City 'vampires' who prey on healthy thirtysomething joggers for their immortalizing blood serum. With the exception of Lupe (San Francisco, CA), the individual storylines of these aforementioned films and novels largely take place in New York City; the protagonist couples are young, upwardly mobile, and acquire choice residency near Central Park (as in Levin's novel, the spacious "classic" floorplan of the Woodhouse couple's Bramford apartment).
Guy and Rosemary decide to conceive their first child. On the night they plan to try to conceive, Minnie Castavet stops by with a special treat - chocolate mousse. Although Rosemary eats only a fraction of her portion, she soon begins feeling woozy and dreams that she is being raped by something not human, while her elderly neighbors watch. The next morning, Guy tells her that she just had a bad dream.
Soon after, she discovers she is pregnant; at the same time, Guy's acting career suddenly begins to thrive. The pregnancy is very difficult at first; Rosemary endures terrible, continuous pain. As the months wear on, the pains ease but Rosemary begins to suspect her elderly neighbors are not the kindly souls they appear to be. After receiving a warning from a friend, she discovers her neighbors are the leaders of a coven of witches, and she suspects they are after her child to use it as a sacrifice. However, she is unable to convince anyone to believe her. Eventually, she finds out the horrible truth, that Guy allowed the devil to impregnate her in exchange for a successful career. She is informed that she is the mother of the long-awaited anti-christ born in June 1966