Efficacy and safety of early initiation of eplerenone treatment in patients with acute heart failure (EARLIER trial):
a multicenter, randomized, double-blind, placebo-controlled trial.
Asakura M, Ito S, Yamada T, Saito Y, Kimura K, Yamashina A, Hirayama A, Kobayashi Y, Hanatani A,
Tsujimoto M, Yasuda S, Abe Y, Higashino Y, Tamaki Y, Sugino H, Niinuma H, Okuhara Y, Koitabashi T,
Momomura SI, Asai K, Nomura A, Kawai H, Satoh Y, Yoshikawa T, Hirata KI, Yokoi Y, Tanaka J,
Shibata Y, Maejima Y, Tamaki S, Kawta H, Iwahashi N, Kobayashi M, Higuchi Y, Kada A, Yamamoto H,
Kitakaze M; EARLIER investigators and study coordinators.
Eur Heart J Cardiovasc Pharmacother. 2020 Nov 11:pvaa132. doi: 10.1093/ehjcvp/pvaa132. Online ahead of print.
a multicenter, randomized, double-blind, placebo-controlled trial.
Asakura M, Ito S, Yamada T, Saito Y, Kimura K, Yamashina A, Hirayama A, Kobayashi Y, Hanatani A,
Tsujimoto M, Yasuda S, Abe Y, Higashino Y, Tamaki Y, Sugino H, Niinuma H, Okuhara Y, Koitabashi T,
Momomura SI, Asai K, Nomura A, Kawai H, Satoh Y, Yoshikawa T, Hirata KI, Yokoi Y, Tanaka J,
Shibata Y, Maejima Y, Tamaki S, Kawta H, Iwahashi N, Kobayashi M, Higuchi Y, Kada A, Yamamoto H,
Kitakaze M; EARLIER investigators and study coordinators.
Eur Heart J Cardiovasc Pharmacother. 2020 Nov 11:pvaa132. doi: 10.1093/ehjcvp/pvaa132. Online ahead of print.
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