ジカ熱感染による先天性異常。一般報道では小頭症が前面にでて、視力障害もとさらっと流されることが多いですが、実際にどれぐらいは発生しているのか。報告。
- ブラジルのSalvador, Bahia。Roberto Santos General Hospital
- 小頭症で出産した29児の調査。小頭症の基準は頭囲32センチ未満を採用。
- wide-field digital imaging systemで評価。
- 29例の58眼球中、17眼球(29%)に異常が認められた。29例中の10例。さらにその10例中7例では両眼球に障害。
- 多数見られた所見がfocal pigment mottling of the retina and chorioretinal atrophy 。次いでoptic nerve abnormalities , bilateral iris coloboma
ざっくりとした言い方では、小頭症例の約3割に先天性視覚障害の発生があるということになるでしょうか。かなりな高率です。
Original Investigation | February 09, 2016
Ocular Findings in Infants With Microcephaly Associated With Presumed Zika Virus Congenital Infection in Salvador, Brazil FREE ONLINE FIRST
[+-] Author Affiliations
1Department of Ophthalmology, Hospital Geral Roberto Santos, Salvador, Brazil
2Vision Institute, Department of Ophthalmology, Paulista Medical School, Federal University of São Paulo, São Paulo, Brazil
3Gonçalo Moniz Research Center, Oswaldo Cruz Foundation, Salvador, Brazil
4Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut
2Vision Institute, Department of Ophthalmology, Paulista Medical School, Federal University of São Paulo, São Paulo, Brazil
3Gonçalo Moniz Research Center, Oswaldo Cruz Foundation, Salvador, Brazil
4Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut
JAMA Ophthalmol. Published online February 09, 2016. doi:10.1001/jamaophthalmol.2016.0267