マーズコロナウイルスMERS-CoV関連、WHO症例定義改訂。
- 臨床・疫学・検査上の条件を満たしてはじめて診断される
- 可能性例１
発熱をともなう急性呼吸器症状。臨床・X線・組織学的所見。
および
MERS-CoV検査の検体が得られないか、単一の不適切な検体で陰性にでた
および
MERS-CoV確定例と直接的疫学リンク - 可能性例２
発熱をともなう急性呼吸器症状。臨床・X線・組織学的所見。
および
結論には至らない検査結果（スクリーニングで陽性だが確定に至らない例など）
および
中東の居住者かあるいは、発症前１４日以内にMERS-CoV感染発生国に渡航歴 - 可能性例３
発熱をともなう急性呼吸器症状。臨床・X線・組織学的所見。
および
結論には至らない検査結果（スクリーニングで陽性だが確定に至らない例など）
および
MERS-CoV確定例と直接的な疫学リンク - 確定例
検査にてMERS-CoV確定。
ソースはWHO
http://www.who.int/csr/disease/coronavirus_infections/case_definition/en/index.html
Revised interim case definition for reporting to WHO – Middle East respiratory syndrome coronavirus (MERS-CoV)
Interim case definition as of 03 July 2013
-
Probable case
Three combinations of clinical, epidemiological and laboratory criteria can define a probable case:
- A person with a febrile acute respiratory illness with clinical, radiological, or histopathological evidence of pulmonary parenchymal disease (e.g. pneumonia or Acute Respiratory Distress Syndrome)
AND
Testing for MERS-CoV is unavailable or negative on a single inadequate specimen1
AND
The patient has a direct epidemiologic-link with a confirmed MERS-CoV case2. - A person with a febrile acute respiratory illness with clinical, radiological, or histopathological evidence of pulmonary parenchymal disease (e.g. pneumonia or Acute Respiratory Distress Syndrome)
AND
An inconclusive MERS-CoV laboratory test (that is, a positive screening test without confirmation)3
AND
A resident of or traveler to Middle Eastern countries where MERS-CoV virus is believed to be circulating in the 14 days before onset of illness. - A person with an acute febrile respiratory illness of any severity
AND
An inconclusive MERS-CoV laboratory test (that is, a positive screening test without confirmation)3
AND
The patient has a direct epidemiologic-link with a confirmed MERS-CoV case2.
Confirmed case
A person with laboratory confirmation of MERS-CoV infection4
- A person with a febrile acute respiratory illness with clinical, radiological, or histopathological evidence of pulmonary parenchymal disease (e.g. pneumonia or Acute Respiratory Distress Syndrome)
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