FRAZE.IT
perform one's duty
carry out one's duty
implement a list of duties
US20030022921
"U.S. Pat. No. 4,822,807 further describes(記載)that when torsemide modification II is present in very finely divided form in pharmaceutical tablets, it rearranges into torsemide modification I, with the result that(結果)the rate of dissolution of the active material upon(時、すると)introducing the tablets into water can be significantly changed. The dissolution rate is an important characteristics of a pharmaceutical dosage form and, in order to dose(服用、投薬)reproducibly(再現性良く), must not differ from one tablet to the next.
[0008] There remains a need in the art for(必要、需要、求め)pharmaceutical formulations containing torsemide modification II, wherein the torsemide modification II does not rearrange into torsemide modification I and remains stable with regard to dissolution rate.