WO2014064400(特表2016-500907)
"From an API source perspective, the combination of a close-coupled impactor（密結合インパクター）which also serves as a charged ionization surface provides the basis of a sensitive multimode ionization source. The spray tip（スプレーチップ）and micro target are preferably configured in close proximity with a glancing impact geometry which results in increased spray flux（噴霧束）at the target and significantly less beam divergence or reflected dispersion when compared to a known broad area SACI ion source."
"According to an embodiment the inner diameter of the liquid capillary tube 3 is 130 μηη and the outer diameter of the liquid capillary tube 3 is 270 μηη. The inner diameter of the second (gas) capillary tube 4 is preferably 330 μηη. This arrangement produces a nebulised spray（噴霧スプレー）which contains droplets with a typical diameter of 10-20 μηη and which have velocities greater than 100 m/s at a close distance from the sprayer tip（スプレーヤーチップ）."
"According to the preferred embodiment the mesh wire size and spacing is preferably sized appropriately so as to provide several discrete impact zones within the impact zone or area. The wire diameter is preferably sufficient so as to allow the impact of the plume on the wire to improve nebulisation（噴霧）."
WO2012100120(特表2014-515861)
"2. The system according to claim 1, wherein the probe comprises a spray emitter（スプレー放射体）and a high voltage source, wherein the probe is configured such that the high voltage source is not in contact with spray（スプレー）emitted by the spray emitter."
WO2011163632(特表2013-534826)
"Selection of ΤΠ Transformed Plants: T\seed was sown on 10.5" x 21" germination trays (T.O. Plastics Inc., Clearwater, MN) as described above and grown under the conditions outlined. The domes were removed 5-6 days post-sowing. 5 days post-sowing, and again 10 days post-sowing, seedlings（苗）were sprayed with（噴霧）a 0.20% solution of glufosinate herbicide (Liberty) in a spray volume（噴霧量）of 10 mL/tray (703 L/ha) using a DeVilbiss compressed air spray tip（スプレーチップ）to deliver an effective rate of 280 g/ha glufosinate per application. 10 mL of the glufosinate herbicide solution was pipetted into（分注）a 20 mL scintillation vial for each tray to be sprayed. The spray was delivered using a horizontal and vertical application pattern. After each spray（スプレー）, a spray label with the herbicide name, application rate, and application date was added to each selection tray. 4 to 7 days after the second spray, herbicide-resistant plants were identified and transplanted into pots prepared with Sunshine mix LP5. Transplanted plants were placed in a greenhouse with the above mentioned growth conditions. Six to eight weeks after transplanting, the seed from each plant was harvested and stored separately with a unique identification number."
WO2016081475(特表2018-501201)
"FIGURE 7 shows particle size distribution of micronized（微粒子化）/lactose blend combination, which is determined by Next Generation Impactor (NGI)"
"According to some other embodiments, the dry powder is produced by micronization（微粒子化）"
"The term "nebulizer（ネブライザー）" as used herein refers to a device used to administer liquid medication in the form of a mist（霧）inhaled into the lungs."
WO2016061611(特表2017-532581)
"Clotting agents or coagulants are classified as either intrinsic clotting agents or extrinsic clotting agents according to the blood cascade stimulated (see for example US patent no. 6,686,204). Suitable clotting agents include, but are not limited to, diatomaceous earth, microparticles or particles of inorganic silicates, microsilica, glass microparticles, ellagic acid, thrombin, heparinase, thromboplastin, batroxobin, hydroyapitite, kaolin, kaolin particles, prothrombin (including microparticulated（微粒子化された）prothrombin), fibrinogen, and depolymerised collagen."
WO2016025911(特表2017-524743)
"16. The method according to claim 15, wherein the bioactive agent, prior to step (b), is micronized（微粒子化）by a process selected from the group consisting of solvent evaporation, hot melt particle formation, solvent removal, spray drying, phase inversion, coacervation, low temperature casting, and film casting."
WO2016014586(特表2017-521181)
"Prior art dry powder inhalers (DPIs) usually have a means for introducing the drug (active drug plus carrier) into a high velocity air stream. The high velocity air-stream is used as the primary mechanism for breaking up the cluster of micronized（微粒子化）particles or separating the drug particles from the carrier. Several inhalation devices useful for dispensing this powder form of medication are known in the prior art."
WO2012052459(特表2013-544794)
"Generally, pharmaceutical compositions suitable for intranasal or inhaled administration may conveniently be formulated as aerosols, solutions, suspensions, drops, gels or dry powders, with one or more pharmaceutically acceptable（薬学的に許容される）carriers and/or excipients such as aqueous or non-aqueous vehicles, thickening agents, isotonicity adjusting agents, antioxidants and/or preservatives. For compositions suitable for intranasal or inhaled administration, the compound of formula (I) or a prodrug thereof, or a pharmaceutically acceptable salt thereof, may typically be in a particle-size-reduced form, which may be prepared by conventional techniques, for example, micronisation（微粒子化）and milling（粉砕）. Generally, the size-reduced (e.g. micronised（微粒子化）) compound of formula (I) or a prodrug thereof, or a pharmaceutically acceptable salt thereof, can be defined by a D50 value of about 0.5 to 10 microns, such as of about 2 to 4 microns (for example as measured using laser diffraction)."
"An example of a cosolvent includes, but is not limited to ethanol. Aerosol compositions may be presented in single or multidose quantities in sterile form in a sealed container, which may take the form of a cartridge or refill for use with an atomising device（霧化装置）or inhaler. Alternatively, the sealed container may be a unitary dispensing device such as a single dose nasal inhaler or an aerosol dispenser fitted with（取り付けられた）a metering valve (metered dose inhaler), which is intended for disposal once the contents of the container have been exhausted."
