Eric E.Schadt, Cheng Li, Byron Ellis, and Wing H.Wong
Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data
Journal of Cellular Biochemistry Supplement 37:120-125(2001)
[PDF][Web Site]
・マイクロアレイデータ解析用ソフト、DNA-Chip Analyzer(dChip)の性能を検証する。
・発現量数値化法(Feature extraction)の比較:APS (adaptive pixel selection) algorithm と TP75 (75th percentile) algorithm (従来法)を比較。
・正規化法の比較
1.Linear normalization (LN)
2.Smoothing spline normalization (GCVSS)
3.Invariant difference selection/smoothing spline (IDS) methods (←提案法)
Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data
Journal of Cellular Biochemistry Supplement 37:120-125(2001)
[PDF][Web Site]
・マイクロアレイデータ解析用ソフト、DNA-Chip Analyzer(dChip)の性能を検証する。
・発現量数値化法(Feature extraction)の比較:APS (adaptive pixel selection) algorithm と TP75 (75th percentile) algorithm (従来法)を比較。
・正規化法の比較
1.Linear normalization (LN)
2.Smoothing spline normalization (GCVSS)
3.Invariant difference selection/smoothing spline (IDS) methods (←提案法)